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Faecal samples enable early detection of colorectal cancer mutations

Published online: 19.12.2025

Whereas colonoscopy worldwide has been established as the standard gold method for detecting colorectal cancer (CRC), the error ratio is extremely high. To evaluate an alternative less invasive method therefore is outmost relevant.

News

Faecal samples enable early detection of colorectal cancer mutations

Published online: 19.12.2025

Whereas colonoscopy worldwide has been established as the standard gold method for detecting colorectal cancer (CRC), the error ratio is extremely high. To evaluate an alternative less invasive method therefore is outmost relevant.

In our new study, published in Scientific Reports, one of the most interesting findings is that human faecal samples can be used as an alternative method for the early detection and characterization of CRC mutations in patients.

More research and replication studies are needed, but this study offers the first evidence for establishing a new molecular based method for detecting CRC with a much lower error ratio, cost and without causing any discomfort to patients.

Authors

Alonzo Alfaro-Núñez
Stina Christensen
Jette Ellehauge
Jens Ole Eriksen
Gitte Andersen
Esther A. Jensen